Endocrine Abstracts

Introduction: The prevalence of non-communicable disorders such as metabolic syndrome (MetS) is high in developing countries. MetS is a disorder of energy utilisation and storage, diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low HDL cholesterol levels. The present review aims to discover the genetic variant reported in a...

Objective: The aim of this study was the assessment of association of two single nucleotide polymorphism (SNP) of thyroid peroxidase (TPO) gene with anti TPO antibody titer for the first time.Materials and methods: In this case–control study, peripheral blood samples of 428 individuals, 178 men (29–76 y) and 250 women (21–76 y) from unrelated families were genotyped (G1201T of exon 8 and A2257C of exon 12) by PCR amplification and RLFP met...

Introduction: High sensitive CRP (hsCRP) has been reported to associate with an increased risk of cardiovascular disease. There is some evidence on apoE polymorphism in relation to the parameters of inflammation. We have investigated the association between APOE genotypes and hsCRP levels in an Iranian population.Materials and methods: We performed a cross-sectional study of 966 subjects (419 men and 547 women) from the Tehran Lipid and Glucose Study. hs...